The Yale Human Research Protection Program provides administrative and regulatory support to 4 Institutional Review Boards (IRBs) for biomedical research known as Human Investigation Committee (HIC I, HIC II, HIC III, HIC IV) and one IRB for social, behavioral and educational research known as Human Subjects Committee (HSC).
As explained on the Human Research website, Yale has made a commitment to ensure that all Yale research complies with federal and state regulations, University policy, and the highest ethical standards. You can also see this as an opportunity to reflect upon your research from different perspectives to make sure that you are being as ethical and responsible as possible in your methodology and approach.
If you are applying for, or have been awarded a fellowship, this decision tree may help you determine whether your research requires IRB or exemption. Please note, you cannot determine exemption for yourself. Exemption must be applied for and can only be granted by the IRB.
Also, be sure to check the Human Research website for an overview on how to approach the IRB application process.
If your project requires IRB review, it means that you will need to go through the Institutional Review Board that is relevant to your project to seek approval or exemption, before you can start your research and before a fellowship check can be released to you. For CIPE fellowships, this is usually the Human Subjects Committee (HSC). If your research will involve animals, please go here for further details.
At certain times of the year, such as the spring semester, the IRB has to process lots of applications from all over Yale. Some CIPE fellowships (such as the Global Health fellowships and the Junior Research fellowships) ask in the application that you start your IRB application before you submit your fellowship award. If that is the case, please start your IRB application as soon as possible to avoid a delay in receiving your fellowship award. For most other fellowships, you should not start your IRB application until you have been notified that you are the recipient of a fellowship award. Please refer to the instructions in your fellowship application for further details.
You are strongly advised to read the "What is the IRB application process" section of this page before you begin.
Once you have read the information below, the Human Research website has some useful guidelines as to how you can prepare to submit an IRB application for review. Go to this page and scroll down to click on "Student Projects" for information specific to undergraduate applications. Once you have started your IRB application, you will be able to access the forms you will need from within the IRES system. The verbal information sheet and written consent forms can be found on this page.
You must read and adhere to this checklist before submitting to avoid your application being returned or delayed.
Check the Fellowships calendar for upcoming IRB information sessions and workshops.
As a Yale student, your research will most likely be supervised by a Yale faculty member. You may need to collaborate with your supervisor, who will very likely be familiar with the IRB process, as you submit your IRB application. Your faculty supervisor will also be required to sign your application protocol. The staff and committee members of the Yale IRBs are very understanding in their approach and recognize that for many undergraduates the IRB process can sound daunting. The resources available on the Human Research website can help you be sure that your application is as complete as possible before you submit it. Once you have submitted your application, the Regulatory Analyst assigned to your application will be in touch with any changes or questions.
Tip: IRB applications cannot be processed until the requirements of steps 1 and 2 have been met.
All students and faculty advisors need to complete Yale's web-based Human Subjects Protection Training.
All students and faculty advisors need to submit a Conflict of Interest Disclosure.
Please contact Sharon Murphy at the Conflict of Interest Office so that an account can be created for you to complete the External Interests Disclosure form. To reach the form, click on “Access the External Interests Disclosure form” on the left side of the Conflict of Interest page. Please note: This is a university requirement and must be fulfilled, regardless of the funding source.
Tip: IRB applications for research funded by fellowships must be submittted via the IRES IRB Submission System.
Important: Read and adhere to this checklist before submitting. Incomplete submissions will be returned and applications which have not been appropriately flagged as fellowships may be delayed.
Once you have completed steps 1 and 2, you will need to submit the following via the IRES IRB Submission System:
Tip: Access to the IRES IRB Submission System requires your NetID and password.
To be able to log in to the IRES IRB Submission System using your NetID, you will need to be registered as a student worker. If you have applied for, or been awarded, a CIPE fellowship, this will be done on your behalf and may take up to 2 working days.
If you are unable to log in to the IRES IRB Submission System, contact email@example.com